Prothrombinase generates thrombosis formation in viral hepatitis infections.

2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Prothrombinase generates thrombosis formation in viral hepatitis infections.

According to a study from Canada, "fibrin deposition and thrombosis within the microvasculature is now appreciated to play a pivotal role in the hepatocellular injury observed in experimental and human viral hepatitis. Importantly, the pathways by which fibrin generation is elicited in viral hepatitis may be mechanistically distinct from the classical pathways of coagulation induced by mechanical trauma or bacterial lipopolysaccharide (LPS)."

"In the setting of murine hepatitis virus strain-3 (MHV-3) infection, a member of the Coronaviridae, …